HOW PKRRATING CAN SAVE YOU TIME, STRESS, AND MONEY.

) mechanism16,30–34 [for your Opposite perspective see35]. The BTB dimer orients the Energetic web pages far from the dimer interface inside of a configuration that cannot mediate this response. Here, we report structures of wild-sort, unphosphorylated PKR kinase. The kinase domains interact by means of the BTB interface and adopt an active confo